Ionis Pharmaceuticals, Inc.
IONS
Rank in Stocks
#2563
Founded in 1989 and headquartered in Carlsbad, California, Ionis... Founded in 1989 and headquartered in Carlsbad, California, Ionis Pharmaceuticals, Inc. is a biopharmaceutical company specializing in the discovery and development of RNA-targeted therapies within the United States. Its commercial portfolio includes three key medications: SPINRAZA, prescribed for spinal muscular atrophy (SMA) in both children and adults; TEGSEDI, an injectable treatment targeting polyneuropathy associated with hereditary transthyretin-mediated amyloidosis in adult patients; and WAYLIVRA, which addresses familial chylomicronemia syndrome and familial partial lipodystrophy. Ionis also maintains a robust pipeline, with several drug candidates currently in Phase 3 clinical trials. These include Eplontersen, a monthly self-administered subcutaneous injection designed for all forms of TTR amyloidosis; Olezarsen, intended for individuals with severe hypertriglyceridemia (SHTG); Donidalorsen, for patients suffering from hereditary angioedema; ION363, aimed at amyotrophic lateral sclerosis (ALS); Pelacarsen, developed for those with established cardiovascular disease and elevated lipoprotein(a); and Tofersen, which works by inhibiting the production of superoxide dismutase 1. Beyond these late-stage assets, the company is actively researching treatments for metabolic, infectious, renal, and ophthalmic diseases, as well as various types of cancer. The firm engages in significant collaborations, notably a strategic partnership with Biogen Inc. Additionally, it holds licensing and collaboration agreements with AstraZeneca, Bayer AG, GlaxoSmithKline plc, Novartis AG, Roche, Janssen Biotech, Inc., and Flamingo Therapeutics, Inc.
Share Price
$45.00
Market Cap
$7.48B
Change (1 day)
1.40%
Change (1 year)
-38.82%
Country
US
Trade Ionis Pharmaceuticals, Inc. (IONS)
Category
Healthcare
P/E ratio for Ionis Pharmaceuticals, Inc. (IONS)
P/E ratio as of October 2026 TTM: -12.34
According to Ionis Pharmaceuticals, Inc. latest financial reports and stock price the company's current price-to-earnings ratio (TTM) is -12.34. At the end of 2023 the company had a P/E ratio of -19.75.
P/E ratio history for Ionis Pharmaceuticals, Inc. from 2000 to 2026
P/E ratio at the end of each year
| Year | P/E Ratio | Change |
|---|---|---|
| 2026 (TTM) | -12.34 | 7.13% |
| 2024 | -11.52 | -41.69% |
| 2023 | -19.75 | -0.47% |
| 2022 | -19.84 | -86.78% |
| 2021 | -150.06 | 744.55% |
| 2020 | -17.77 | -161.77% |
| 2019 | 28.77 | 10.08% |
| 2018 | 26.13 | -102.50% |
| 2017 | -1.04K | 1,465.31% |
| 2016 | -66.75 | -20.24% |
| 2015 | -83.69 | -55.10% |
| 2014 | -186.39 | 156.76% |
| 2013 | -72.59 | 352.69% |
| 2012 | -16.04 | 89.26% |
| 2011 | -8.47 | -48.27% |
| 2010 | -16.38 | -333.04% |
| 2009 | 7.03 | -106.27% |
| 2008 | -112.09 | -6.56% |
| 2007 | -119.96 | 566.43% |
| 2006 | -18.00 | 295.57% |
| 2005 | -4.55 | 94.05% |
| 2004 | -2.35 | -38.21% |
| 2003 | -3.80 | -23.64% |
| 2002 | -4.97 | -62.51% |
| 2001 | -13.26 | 80.25% |
| 2000 | -7.35 | 0.00% |
P/E ratio for similar companies or competitors
| Company | P/E Ratio | P/E Ratio Difference | Country |
|---|---|---|---|
| 28.78 | -333.22% |
US
|
|
| -28.36 | 129.79% |
US
|
|
| -24.57 | 99.07% |
AU
|
|
| - | - |
CH
|
|
| 30.33 | -345.77% |
NL
|
How to read a P/E ratio?
The Price/Earnings ratio measures the relationship between a company's stock price and its earnings per share.
A low but positive P/E ratio stands for a company that is generating high earnings compared to its current valuation and might be undervalued. A company with a high negative (near 0) P/E ratio stands for a company that is generating heavy losses compared to its current valuation.
Companies with a P/E ratio over 30 or a negative one are generaly seen as "growth stocks" meaning that investors typically expect the company to grow or to become profitable in the future.
Companies with a positive P/E ratio bellow 10 are generally seen as "value stocks" meaning that the company is already very profitable and unlikely to strong growth in the future.