Protagonist Therapeutics, Inc.
PTGX
Rank in Stocks
#2350
Protagonist Therapeutics, Inc. is a biopharmaceutical firm dedicated to... Protagonist Therapeutics, Inc. is a biopharmaceutical firm dedicated to discovering and advancing peptide-based therapies. Their research primarily focuses on treatments for hematological and blood conditions, as well as inflammatory and immune-mediated disorders. The company's pipeline features rusfertide (PTG-300), an injectable hepcidin mimetic currently undergoing Phase II clinical trials for the management of polycythemia vera, hereditary hemochromatosis, and other blood-related ailments. Also in Phase II development is PN-943, an oral peptide engineered as a specific antagonist of alpha-4-beta-7 integrin, intended for addressing inflammatory bowel disease (IBD). Furthermore, they are progressing PN-235, an orally administered antagonist specifically targeting the interleukin-23 receptor, designed for both IBD and various non-IBD therapeutic applications. Protagonist Therapeutics maintains a licensing and collaborative agreement with Janssen Biotech, Inc. Founded in 2006, the company's headquarters are located in Newark, California.
Share Price
$129.52
Last synced: 2026-10-16
Market Cap
$8.38B
Change (1 day)
-5.15%
Change (1 year)
67.12%
Country
US
Trade Protagonist Therapeutics, Inc. (PTGX)
Category
Healthcare
Operating Margin for Protagonist Therapeutics, Inc. (PTGX)
Operating Margin as of October 2026 TTM: 20.69%
According to Protagonist Therapeutics, Inc. latest financial reports and stock price the company's current Operating Margin (TTM) is 20.69%. At the end of 2023 the company had an Operating Margin of -156.09%.
Operating Margin history for Protagonist Therapeutics, Inc. from 2014 to 2026
Operating Margin at the end of each year
| Year | Operating Margin | Change |
|---|---|---|
| 2026 (TTM) | 20.69% | -64.45% |
| 2024 | 58.20% | -137.29% |
| 2023 | -156.09% | -68.42% |
| 2022 | -494.24% | 7.44% |
| 2021 | -460.01% | 104.12% |
| 2020 | -225.36% | -99.35% |
| 2019 | -34,857.58% | 25,403.06% |
| 2018 | -136.68% | -27.64% |
| 2017 | -188.89% | 0.00% |
| 2016 | 0.00% | 0.00% |
| 2015 | 0.00% | 0.00% |
| 2014 | 0.00% | 0.00% |
Operating Margin for similar companies or competitors
| Company | Operating Margin | Operating Margin Difference | Country |
|---|---|---|---|
| 38.59% | -98.13% |
US
|
|
| -149.01% | -107.20% |
US
|
|
| 25.57% | -98.76% |
AU
|
|
| 0.00% | - |
CH
|
|
| 28.81% | -98.61% |
NL
|
What is a company's Operating Margin?
The operating margin is a key indicator to assess the profitability of a company. Higher operating margins are generaly better as they show that a company is able to sell its products or services for much more than their production costs. The operating margin is calculated by dividing a company's earnings by its revenue.