Prime Medicine, Inc.
PRME
Rank in Stocks
#9847
Prime Medicine, Inc. operates as a biotechnology firm, dedicated to delivering... Prime Medicine, Inc. operates as a biotechnology firm, dedicated to delivering genetic therapies for various diseases by strategically employing advanced gene editing technology. Central to their platform is the "Prime Editor" system, which combines a unique Prime Editor protein—a hybrid composed of a Cas protein and a reverse transcriptase enzyme—with a specialized pegRNA molecule. This pegRNA plays a crucial role by both guiding the Prime Editor to a precise location within the genome and providing the essential template for introducing the desired modification to the target DNA sequence. The company, founded in 2019, maintains its headquarters in Cambridge, Massachusetts.
Share Price
$4.30
Last synced: 2026-11-09
Market Cap
$779.92M
Change (1 day)
-7.53%
Change (1 year)
9.69%
Country
Stock data: Financial Modeling Prep·Updated ·Not investment advice·How we calculate this
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Category
Healthcare
Operating Margin for Prime Medicine, Inc. (PRME)
Operating Margin as of November 2026 TTM: -4,824.94%
According to Prime Medicine, Inc.'s latest financial reports, its current operating margin (TTM) is -4,824.94%. At the end of 2025 the company had an operating margin of -4,498.06%.
Operating Margin history for Prime Medicine, Inc. from 2019 to 2026
Operating Margin at the end of each year
| Year | Operating Margin | Change |
|---|---|---|
| 2026 (TTM) | -4,824.94% | 7.27% |
| 2025 | -4,498.06% | -33.73% |
| 2024 | -6,787.36% | 0.00% |
| 2023 | 0.00% | 0.00% |
| 2022 | 0.00% | 0.00% |
| 2021 | 0.00% | -100.00% |
| 2020 | -17.89% | 0.00% |
| 2019 | 0.00% | 0.00% |
Operating Margin for similar companies or competitors
| Company | Operating Margin | Operating Margin Difference | Country |
|---|---|---|---|
| 38.59% | -100.01% |
US
|
|
| -149.01% | -99.97% |
US
|
|
| 25.57% | -100.01% |
AU
|
|
| 31.23% | -100.01% |
BE
|
|
| 29.35% | -100.01% |
NL
|
What is a company's Operating Margin?
The operating margin is a key indicator to assess the profitability of a company. Higher operating margins are generaly better as they show that a company is able to sell its products or services for much more than their production costs. The operating margin is calculated by dividing a company's earnings by its revenue.
Questions about Prime Medicine, Inc.'s operating margin
What is Prime Medicine, Inc.'s operating margin?
Prime Medicine, Inc.'s operating margin is -4,824.94%, as of Nov 2026.
What was Prime Medicine, Inc.'s operating margin in 2025?
In 2025, Prime Medicine, Inc.'s operating margin was -4,498.06%, compared with -6,787.36% in 2024.
How has Prime Medicine, Inc.'s operating margin changed since 2020?
From 2020 to 2025, Prime Medicine, Inc.'s operating margin was highest in 2023 (0.00%) and lowest in 2024 (-6,787.36%).
How does Prime Medicine, Inc.'s operating margin compare with similar companies?
Prime Medicine, Inc.'s operating margin (-4,824.94%) is lower than that of all 5 similar companies listed above. The highest among them is Vertex Pharmaceuticals Incorporated, with 38.59%.