Exelixis, Inc.
EXEL
Rank in Stocks
#1429
Exelixis, Inc. operates as a biotechnology firm dedicated to combating cancer,... Exelixis, Inc. operates as a biotechnology firm dedicated to combating cancer, primarily focusing on the identification, advancement, and marketing of novel oncological treatments within the United States. Its portfolio of commercially available therapeutics includes CABOMETYX tablets, prescribed for individuals with advanced renal cell carcinoma who have previously undergone anti-angiogenic treatment, and COMETRIQ capsules, utilized for managing progressive and metastatic medullary thyroid cancer. Both CABOMETYX and COMETRIQ originate from cabozantinib, a compound that inhibits several tyrosine kinases such as MET, AXL, RET, and VEGF receptors. Additionally, Exelixis offers COTELLIC, an MEK inhibitor employed in combination therapies for advanced melanoma, and MINNEBRO, an orally administered, non-steroidal selective mineralocorticoid receptor blocker, approved for hypertension treatment in Japan. The company's developmental pipeline features several promising candidates, such as XL092, an oral tyrosine kinase inhibitor designed to target VEGF receptors, MET, AXL, MER, and other kinases crucial for cancer proliferation; XB002, an antibody-drug conjugate containing a human monoclonal antibody against tissue factor (TF), intended for advanced solid tumors and non-Hodgkin's lymphoma; and XL102, an orally available cyclin-dependent kinase 7 (CDK7) inhibitor being developed for advanced or metastatic solid tumors. Exelixis, Inc. maintains extensive research partnerships and licensing arrangements with numerous pharmaceutical and biotechnology entities, including Ipsen Pharma SAS, Takeda Pharmaceutical Company Ltd., F. Hoffmann-La Roche Ltd., Redwood Bioscience, Inc., R.P. Scherer Technologies, LLC, Catalent Pharma Solutions, Inc., NBE Therapeutics AG, Aurigene Discovery Technologies Limited, Iconic Therapeutics, Inc., Invenra, Inc., StemSynergy Therapeutics, Inc., Genentech, Inc., Bristol-Myers Squibb Company, and Daiichi Sankyo Company, Limited. Established in 1994, the company originally operated as Exelixis Pharmaceuticals, Inc. before rebranding to Exelixis, Inc. in February 2000. Its corporate headquarters are located in Alameda, California.
Share Price
$61.84
Last synced: 2026-10-16
Market Cap
$15.54B
Change (1 day)
-1.58%
Change (1 year)
57.55%
Country
US
Trade Exelixis, Inc. (EXEL)
Category
Healthcare
Operating Margin for Exelixis, Inc. (EXEL)
Operating Margin as of October 2026 TTM: 39.88%
According to Exelixis, Inc. latest financial reports and stock price the company's current Operating Margin (TTM) is 39.88%. At the end of 2025 the company had an Operating Margin of 27.88%.
Operating Margin history for Exelixis, Inc. from 2000 to 2026
Operating Margin at the end of each year
| Year | Operating Margin | Change |
|---|---|---|
| 2026 (TTM) | 39.88% | 43.04% |
| 2025 | 27.88% | 198.50% |
| 2023 | 9.34% | -25.34% |
| 2022 | 12.51% | -37.39% |
| 2021 | 19.98% | -47.67% |
| 2020 | 38.18% | -25.72% |
| 2018 | 51.40% | 40.17% |
| 2017 | 36.67% | -349.63% |
| 2016 | -14.69% | -98.36% |
| 2014 | -893.86% | 39.55% |
| 2013 | -640.54% | 148.24% |
| 2012 | -258.03% | -934.78% |
| 2011 | 30.91% | -162.58% |
| 2010 | -49.39% | -67.54% |
| 2009 | -152.14% | 9.93% |
| 2007 | -138.40% | 7.74% |
| 2006 | -128.46% | 3.81% |
| 2005 | -123.74% | -51.62% |
| 2004 | -255.79% | 36.95% |
| 2003 | -186.77% | -5.74% |
| 2002 | -198.15% | 7.88% |
| 2001 | -183.67% | 6.09% |
| 2000 | -173.12% | 0.00% |
Operating Margin for similar companies or competitors
| Company | Operating Margin | Operating Margin Difference | Country |
|---|---|---|---|
| 38.59% | -99.03% |
US
|
|
| -149.01% | -103.74% |
US
|
|
| 25.57% | -99.36% |
AU
|
|
| 0.00% | - |
CH
|
|
| 28.81% | -99.28% |
NL
|
What is a company's Operating Margin?
The operating margin is a key indicator to assess the profitability of a company. Higher operating margins are generaly better as they show that a company is able to sell its products or services for much more than their production costs. The operating margin is calculated by dividing a company's earnings by its revenue.