CRISPR Therapeutics AG
CRSP
Rank in Stocks
#3587
CRISPR Therapeutics AG (CRSP) is a biotechnology firm dedicated to pioneering... CRISPR Therapeutics AG (CRSP) is a biotechnology firm dedicated to pioneering gene-based medicines for severe diseases. The company achieves this through its exclusive Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/CRISPR-associated protein 9 (Cas9) technology, which enables precise and targeted alterations to an organism's genetic code. Its extensive pipeline includes therapeutic candidates spanning multiple medical areas, such as blood disorders (hemoglobinopathies), various cancers (oncology), regenerative medicine, and rare conditions. The company's flagship investigational therapy is CTX001, an ex vivo CRISPR gene-edited treatment. This therapy aims to benefit patients with transfusion-dependent beta-thalassemia or severe sickle cell disease by modifying their own hematopoietic stem cells to markedly boost the production of fetal hemoglobin within red blood cells. CRISPR Therapeutics is also advancing several other genetically engineered allogeneic (donor-sourced) CAR-T investigational therapies: CTX110, designed to combat cluster of differentiation 19-positive malignancies; CTX120, which targets B-cell maturation antigen for multiple myeloma that has relapsed or proven resistant to previous treatments; and CTX130, focused on Cluster of Differentiation 70 for a spectrum of solid tumors and blood cancers. Furthermore, the company is developing VCTX210, an immune-evasive, gene-edited stem cell-derived product candidate for treating type 1 diabetes. It is also pursuing various in vivo gene-editing initiatives aimed at addressing disorders affecting the liver, lungs, muscles, and central nervous system. The company has forged strategic alliances with significant partners, including Bayer Healthcare LLC, Vertex Pharmaceuticals Incorporated, ViaCyte, Inc., Nkarta, Inc., and Capsida Biotherapeutics. CRISPR Therapeutics AG was established in 2013 and maintains its headquarters in Zug, Switzerland.
Share Price
$49.25
Last synced: 2026-10-16
Market Cap
$4.76B
Change (1 day)
-4.42%
Change (1 year)
-28.78%
Country
CH
Trade CRISPR Therapeutics AG (CRSP)
Category
Healthcare
Operating Margin for CRISPR Therapeutics AG (CRSP)
Operating Margin as of October 2026 TTM: -3,971.53%
According to CRISPR Therapeutics AG latest financial reports and stock price the company's current Operating Margin (TTM) is -3,971.53%. At the end of 2023 the company had an Operating Margin of -59.95%.
Operating Margin history for CRISPR Therapeutics AG from 2014 to 2026
Operating Margin at the end of each year
| Year | Operating Margin | Change |
|---|---|---|
| 2026 (TTM) | -3,971.53% | 197.93% |
| 2024 | -1,333.05% | 2,123.60% |
| 2023 | -59.95% | -99.96% |
| 2022 | -154,394.72% | -377,500.93% |
| 2021 | 40.91% | -100.06% |
| 2020 | -65,273.48% | -404,520.57% |
| 2019 | 16.14% | -100.32% |
| 2018 | -5,087.80% | 3,126.46% |
| 2017 | -157.69% | -88.05% |
| 2016 | -1,319.33% | -87.33% |
| 2015 | -10,416.60% | 0.00% |
| 2014 | 0.00% | 0.00% |
Operating Margin for similar companies or competitors
| Company | Operating Margin | Operating Margin Difference | Country |
|---|---|---|---|
| 38.59% | -100.01% |
US
|
|
| -149.01% | -99.96% |
US
|
|
| 25.57% | -100.01% |
AU
|
|
| 0.00% | - |
CH
|
|
| 28.81% | -100.01% |
NL
|
What is a company's Operating Margin?
The operating margin is a key indicator to assess the profitability of a company. Higher operating margins are generaly better as they show that a company is able to sell its products or services for much more than their production costs. The operating margin is calculated by dividing a company's earnings by its revenue.