Arrowhead Pharmaceuticals, Inc.
ARWR
Rank in Stocks
#2464
Arrowhead Pharmaceuticals, Inc., founded in 1989 and based in Pasadena,... Arrowhead Pharmaceuticals, Inc., founded in 1989 and based in Pasadena, California, is a biopharmaceutical company dedicated to discovering and advancing innovative treatments for complex and challenging-to-treat diseases within the United States. The company's extensive therapeutic pipeline primarily leverages RNA interference (RNAi) technology. Among its advanced clinical programs are: ARO-AAT, a Phase II therapeutic targeting liver diseases associated with alpha-1 antitrypsin deficiency; ARO-APOC3, which is undergoing both Phase 2b and Phase 3 clinical evaluations for hypertriglyceridemia; ARO-ANG3, currently in Phase 2b development to reduce the production of angiopoietin-like protein 3; and ARO-HIF2, a Phase 1b candidate designed to treat clear cell renal cell carcinoma. Arrowhead also has several compounds in earlier clinical development, including ARO-HSD in Phase 1/2a for other liver diseases, ARO-ENaC in Phase 1/2a, aimed at decreasing the epithelial sodium channel alpha subunit in lung airways, and ARO-C3, also in Phase 1/2a, for complement-mediated diseases. Further expanding its diverse portfolio, the company is actively developing ARO-Lung2 for chronic obstructive pulmonary disorder (COPD), ARO-DUX4 for facioscapulohumeral muscular dystrophy, ARO-XDH for uncontrolled gout, and ARO-COV for COVID-19 and other pulmonary-borne pathogens. Beyond its core internal programs, Arrowhead is involved in the progression of JNJ-3989, a subcutaneously administered RNAi therapeutic for chronic hepatitis B virus infection; Olpasiran, intended to reduce apolipoprotein A production; and ARO-AMG1, which targets genetically validated cardiovascular pathways. Strategic collaborations are integral to Arrowhead's development efforts. The company holds a licensing and research agreement with Janssen Pharmaceuticals, Inc. for the co-development of ARO-JNJ1, ARO-JNJ2, and ARO-JNJ3, all RNAi therapeutics focused on liver-expressed targets. Additionally, Arrowhead has a licensing and research partnership with Takeda Pharmaceuticals U.S.A., Inc. to develop an RNAi therapeutic candidate specifically for liver disease.
Share Price
$56.16
Last synced: 2026-10-16
Market Cap
$7.93B
Change (1 day)
-4.00%
Change (1 year)
52.56%
Country
US
Trade Arrowhead Pharmaceuticals, Inc. (ARWR)
Category
Healthcare
Operating Margin for Arrowhead Pharmaceuticals, Inc. (ARWR)
Operating Margin as of October 2026 TTM: -33.82%
According to Arrowhead Pharmaceuticals, Inc. latest financial reports and stock price the company's current Operating Margin (TTM) is -33.82%. At the end of 2024 the company had an Operating Margin of -16,927.06%.
Operating Margin history for Arrowhead Pharmaceuticals, Inc. from 2000 to 2026
Operating Margin at the end of each year
| Year | Operating Margin | Change |
|---|---|---|
| 2026 (TTM) | -33.82% | -385.16% |
| 2025 | 11.86% | -100.07% |
| 2024 | -16,927.06% | 19,776.77% |
| 2023 | -85.16% | 16.04% |
| 2022 | -73.39% | -31.90% |
| 2021 | -107.77% | 1.79% |
| 2020 | -105.87% | -392.06% |
| 2019 | 36.25% | -110.46% |
| 2018 | -346.52% | 194.18% |
| 2017 | -117.79% | -99.77% |
| 2016 | -51,627.09% | 105.49% |
| 2015 | -25,124.08% | -17.47% |
| 2014 | -30,443.59% | 259.37% |
| 2013 | -8,471.29% | -41.00% |
| 2012 | -14,358.61% | 332.56% |
| 2011 | -3,319.48% | 133.86% |
| 2010 | -1,419.46% | 172.73% |
| 2009 | -520.47% | -80.62% |
| 2008 | -2,685.89% | -14.50% |
| 2007 | -3,141.43% | -8.68% |
| 2006 | -3,439.94% | 111.82% |
| 2005 | -1,624.03% | 18.48% |
| 2004 | -1,370.73% | 0.00% |
| 2003 | 0.00% | -100.00% |
| 2002 | -62,498.41% | 5,376.74% |
| 2001 | -1,141.16% | 159.90% |
| 2000 | -439.08% | 0.00% |
Operating Margin for similar companies or competitors
| Company | Operating Margin | Operating Margin Difference | Country |
|---|---|---|---|
| 38.59% | -101.14% |
US
|
|
| -149.01% | -95.59% |
US
|
|
| 25.57% | -100.76% |
AU
|
|
| 0.00% | - |
CH
|
|
| 28.81% | -100.85% |
NL
|
What is a company's Operating Margin?
The operating margin is a key indicator to assess the profitability of a company. Higher operating margins are generaly better as they show that a company is able to sell its products or services for much more than their production costs. The operating margin is calculated by dividing a company's earnings by its revenue.