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Ensysce Biosciences, Inc. Ensysce Biosciences, Inc.

Ensysce Biosciences, Inc.

ENSC
Rank in Stocks #36735
Ensysce Biosciences, Inc. is a clinical-stage pharmaceutical firm dedicated to... Ensysce Biosciences, Inc. is a clinical-stage pharmaceutical firm dedicated to developing novel prescription drugs for the treatment of severe pain in the United States, with a specific focus on preventing opioid addiction, misuse, abuse, and overdose. The company leverages two primary technological frameworks: the Trypsin Activated Abuse Protection (TAAP) platform, which creates opioid prodrugs designed to resist abuse, and the Multi-Pill Abuse Resistance (MPAR) platform, engineered to offer protection against overdose through its advanced opioid prodrug technology. Ensysce's pipeline features several key candidates, including PF614, an oxycodone prodrug developed using the TAAP platform, currently undergoing Phase II clinical trials for both acute and chronic pain management. Another product, PF614-MPAR, is a combination of PF614 and nafamostat, in Phase I clinical development to provide overdose protection against excessive oral consumption. Furthermore, the company is exploring an oral and inhaled formulation of nafamostat for potential use against coronaviral infections and other pulmonary diseases, such as cystic fibrosis. The company's development efforts also include PF329, an extended-release hydromorphone prodrug similar to PF614. In the area of ADHD treatment, Ensysce is advancing PF8001 and PF8026, which are extended-release and immediate-release amphetamine prodrugs, respectively, aimed at deterring medication abuse. Additionally, PF26810, an extended-release methadone prodrug, is in development for opioid use disorder. Ensysce Biosciences, Inc. operates from its headquarters in La Jolla, California.
Share Price
$0.2483
Last synced: 2026-07-31
Market Cap
$2.30M
Change (1 day)
-3.39%
Change (1 year)
-89.01%
Country
US
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Operating Margin for Ensysce Biosciences, Inc. (ENSC)
Operating Margin as of September 2026 TTM: -1,087.47%
According to Ensysce Biosciences, Inc. latest financial reports and stock price the company's current Operating Margin (TTM) is -1,087.47%. At the end of 2023 the company had an Operating Margin of -480.41%.
Operating Margin history for Ensysce Biosciences, Inc. from 2017 to 2026
Operating Margin at the end of each year
Year Operating Margin Change
2026 (TTM) -1,087.47% 741.89%
2024 -129.17% -73.11%
2023 -480.41% -49.96%
2022 -960.05% 70.61%
2021 -562.73% 1,271.51%
2020 -41.03% -78.26%
2019 -188.72% 0.00%
2018 0.00% 0.00%
2017 0.00% 0.00%
Operating Margin for similar companies or competitors
Company Operating Margin Operating Margin Difference Country
38.59% -100.04%
US
-149.01% -99.86%
US
28.81% -100.03%
NL
25.57% -100.02%
AU
0.00% -
CH
What is a company's Operating Margin?
The operating margin is a key indicator to assess the profitability of a company. Higher operating margins are generaly better as they show that a company is able to sell its products or services for much more than their production costs. The operating margin is calculated by dividing a company's earnings by its revenue.