Dyadic International, Inc.
DYAI
Rank in Stocks
#27961
Dyadic International, Inc. operates as a U.S.-based biotechnology platform... Dyadic International, Inc. operates as a U.S.-based biotechnology platform company, specializing in the development, production, and commercialization of enzymes and other proteins. Its core activities are underpinned by a patented and proprietary C1 platform, alongside other advanced technologies. This technological foundation drives their research, development, and commercial endeavors, focusing on the creation and manufacturing of various human and animal vaccines and pharmaceutical products. These offerings span a wide range of biological therapeutics, including virus-like particles (VLPs), antigens, monoclonal, bi-specific, and tri-specific antibodies, Fab antibody fragments, Fc-fusion proteins, biosimilars, biobetters, and diverse therapeutic enzymes and proteins. A key pipeline asset is DYAI-100, a SARS-CoV-2-RBD antigen vaccine candidate. This candidate is currently slated for a first-in-human Phase 1 clinical trial, with the objective of establishing proof of concept for the development of next-generation, multivariant COVID-19 vaccine candidates. Dyadic also maintains several strategic alliances, including a research and development agreement with VTT Technical Research Centre of Finland, Ltd., a strategic research services agreement with Biotechnology Developments for Industry in Pharmaceuticals, S.L.U., and a collaboration with Syngene International Limited. Established in 1979, the company is headquartered in Jupiter, Florida.
Share Price
$0.3501
Last synced: 2026-11-12
Market Cap
$12.76M
Change (1 day)
-9.77%
Change (1 year)
-61.31%
Country
Stock data: Financial Modeling PrepΒ·Updated Β·Not investment adviceΒ·How we calculate this
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Category
Healthcare
Operating Margin for Dyadic International, Inc. (DYAI)
Operating Margin as of November 2026 TTM: -213.59%
According to Dyadic International, Inc.'s latest financial reports, its current operating margin (TTM) is -213.59%. At the end of 2025 the company had an operating margin of -579.88%.
Operating Margin history for Dyadic International, Inc. from 2003 to 2026
Operating Margin at the end of each year
| Year | Operating Margin | Change |
|---|---|---|
| 2026 (TTM) | -213.59% | -63.17% |
| 2025 | -579.88% | 243.49% |
| 2024 | -168.82% | -40.54% |
| 2023 | -283.90% | -18.17% |
| 2022 | -346.92% | -43.38% |
| 2021 | -612.67% | -2.11% |
| 2020 | -625.85% | 13.34% |
| 2019 | -552.18% | -5.79% |
| 2018 | -586.09% | -37.63% |
| 2017 | -939.70% | -6.45% |
| 2016 | -1,004.45% | -13.03% |
| 2015 | -1,154.93% | 2,616.20% |
| 2014 | -42.52% | -1,408.31% |
| 2013 | 3.25% | -67.50% |
| 2012 | 10.00% | -114.33% |
| 2006 | -69.78% | 10.99% |
| 2005 | -62.87% | 97.58% |
| 2004 | -31.82% | -64.76% |
| 2003 | -90.30% | 0.00% |
Operating Margin for similar companies or competitors
| Company | Operating Margin | Operating Margin Difference | Country |
|---|---|---|---|
| 38.59% | -100.18% |
US
|
|
| -149.01% | -99.30% |
US
|
|
| 25.57% | -100.12% |
AU
|
|
| 31.23% | -100.15% |
BE
|
|
| 29.35% | -100.14% |
NL
|
What is a company's Operating Margin?
The operating margin is a key indicator to assess the profitability of a company. Higher operating margins are generaly better as they show that a company is able to sell its products or services for much more than their production costs. The operating margin is calculated by dividing a company's earnings by its revenue.
Questions about Dyadic International, Inc.'s operating margin
What is Dyadic International, Inc.'s operating margin?
Dyadic International, Inc.'s operating margin is -213.59%, as of Nov 2026.
What was Dyadic International, Inc.'s operating margin in 2025?
In 2025, Dyadic International, Inc.'s operating margin was -579.88%, compared with -168.82% in 2024.
How has Dyadic International, Inc.'s operating margin changed since 2020?
From 2020 to 2025, Dyadic International, Inc.'s operating margin was highest in 2024 (-168.82%) and lowest in 2020 (-625.85%).
How does Dyadic International, Inc.'s operating margin compare with similar companies?
Dyadic International, Inc.'s operating margin (-213.59%) is lower than that of all 5 similar companies listed above. The highest among them is Vertex Pharmaceuticals Incorporated, with 38.59%.