Centessa Pharmaceuticals plc Centessa Pharmaceuticals plc

Centessa Pharmaceuticals plc

CNTA

Rankning i aktier #2957
Centessa Pharmaceuticals plc operates as a clinical-stage pharmaceutical... Centessa Pharmaceuticals plc operates as a clinical-stage pharmaceutical enterprise focused on discovering, developing, and ultimately providing therapeutic solutions to patients. The company's most advanced product candidates include Lixivaptan, a small molecule inhibitor of the vasopressin V2 receptor, which is currently undergoing Phase III clinical evaluation for treating autosomal dominant polycystic kidney disease. Additionally, SerpinPC, an activated protein C inhibitor, is progressing through Phase IIa clinical development for the management of hemophilia A and B. Centessa's pipeline also features several emerging assets in the clinical proof-of-concept stage. These comprise LB101 (a PD-L1xCD47 LockBody) and LB201 (a PD-L1xCD3 LockBody), both engineered to selectively activate potent CD47 and CD3 effector functions while minimizing systemic side effects. Another molecule, ZF874, is a small molecule pharmacological chaperone in Phase I studies, designed to correct the misfolding of the Z variant of alpha-1-antitrypsin, thus addressing alpha-1-antitrypsin deficiency. Furthermore, MGX292, a recombinant modified BMP9 replacement protein, aims to rectify the deficient BMP9 signaling implicated in Pulmonary Arterial Hypertension. The company is also developing OX2R Agonists, which are selective orexin receptor 2 agonists (available as oral and intranasal formulations) intended to directly target the underlying pathophysiology of orexin neuron loss in Narcolepsy Type 1 by leveraging structural insights. Beyond these, Centessa is exploring further clinical proof-of-concept compounds. CBS001, an anti-LIGHT antibody, is being investigated for inflammatory and fibrotic diseases due to its preferential binding to the inflammatory membrane form of LIGHT. Lastly, CBS004 is a humanized monoclonal antibody specifically targeting BDCA2, a protein found exclusively on plasmacytoid dendritic cells, with potential utility in conditions such as systemic sclerosis, systemic lupus erythematosus, and other autoimmune disorders. Centessa Pharmaceuticals plc was established in 2020 and is headquartered in Altrincham, United Kingdom.
Aktiekurs
$40.50
Senast synkroniserad: 2026-06-29
Marknadsvärde
$6.22B
Förändring (1 dag)
0.00%
Förändring (1 år)
75.93%
Land
GB
Handel Centessa Pharmaceuticals plc (CNTA)

Kategori

Healthcare
Rörelsemarginal för Centessa Pharmaceuticals plc (CNTA)
Rörelsemarginal per October 2026 TTM: 0.00%
Enligt de senaste finansiella rapporterna och aktiekursen för Centessa Pharmaceuticals plc är företagets nuvarande rörelsemarginal (TTM) 0.00%. Vid slutet av 2023 var rörelsemarginalen -2,499.39%.
Historik för rörelsemarginal för Centessa Pharmaceuticals plc från 2019 till 2026
Rörelsemarginal vid slutet av varje år
År Rörelsemarginal Ändra
2026 (TTM) 0.00% -100.00%
2024 0.00% -100.00%
2023 -2,499.39% 0.00%
2022 0.00% 0.00%
2021 0.00% 0.00%
2020 0.00% 0.00%
2019 0.00% 0.00%
Rörelsemarginal för liknande företag eller konkurrenter
Företag Rörelsemarginal Skillnad i rörelsemarginal Land
38.59% -
US
-149.01% -
US
25.57% -
AU
0.00% -
CH
28.81% -
NL
Vad är ett företags Rörelsemarginal?
Rörelsemarginal är en viktig indikator för att bedöma ett företags lönsamhet. Högre Rörelsemarginals är generellt bättre eftersom de visar att ett företag kan sälja sina produkter eller tjänster för betydligt mer än produktionskostnaden. Rörelsemarginal beräknas genom att dividera företagets vinst med dess intäkter.