Verastem, Inc.
VSTM
Rang în acțiuni
#10058
Verastem, Inc. is an emerging biopharmaceutical company dedicated to the... Verastem, Inc. is an emerging biopharmaceutical company dedicated to the creation and commercialization of innovative therapeutic agents for cancer treatment. A primary asset in its pipeline is VS-6766, a novel dual RAF/MEK inhibitor that operates by a "clamp" mechanism. This unique action effectively blocks the kinase activity of MEK and disrupts RAF's ability to phosphorylate MEK. The company is actively advancing several clinical trials. RAMP 201 is an adaptive, two-part, multicenter, randomized, open-label study designed to assess both the efficacy and safety of VS-6766, administered alone or in combination with defactinib. Defactinib is an oral small molecule inhibitor of focal adhesion kinase (FAK), and this trial targets patients with recurrent low-grade serous ovarian cancer. Simultaneously, Verastem is conducting RAMP 202, a Phase 2 trial focused on evaluating the safety profile of VS-6766 combined with defactinib. This particular study enrolls patients with non-small cell lung cancer (NSCLC) that harbors KRAS and BRAF mutations, specifically after they have undergone treatment with platinum-based regimens and immune checkpoint inhibitors. Verastem has also forged strategic partnerships to support its development efforts. It holds license agreements with Chugai Pharmaceutical Co., Ltd. for the development, commercialization, and manufacturing rights of products incorporating VS-6766. Additionally, a similar agreement with Pfizer Inc. pertains to the research, development, production, and marketing of Pfizer's FAK inhibitors for various human applications, including therapeutic, diagnostic, and prophylactic uses. Further expanding its collaborations, Verastem has a clinical agreement with Amgen, Inc. to explore the synergistic potential of VS-6766 alongside Amgen's KRAS-G12C inhibitor, LUMAKRAS™, a combination being investigated in the Phase 1/2 RAMP 203 trial. Founded in 2010, Verastem, Inc. maintains its corporate headquarters in Needham, Massachusetts.
Preț acțiune
$9.31
Capitalizare de piață
$843.15M
Schimbare (1 zi)
8.00%
Schimbare (1 an)
8.89%
Țară
US
Tranzacționează Verastem, Inc. (VSTM)
Categorie
Healthcare
Istoricul spliturilor pentru Verastem, Inc. (VSTM)
Acțiunea Verastem, Inc. (simbol: VSTM) a trecut printr-un total de 0 splituri.
Cel mai recent split a avut loc pe Oct 20, 2026.
O acțiune VSTM cumpărată înainte de Oct 20, 2026 este echivalentă astăzi cu 0 acțiuni VSTM.
Cel mai recent split a avut loc pe Oct 20, 2026.
O acțiune VSTM cumpărată înainte de Oct 20, 2026 este echivalentă astăzi cu 0 acțiuni VSTM.
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