Alnylam Pharmaceuticals, Inc.
ALNY
Rang in aandelen
#772
Alnylam Pharmaceuticals, Inc. is a biopharmaceutical company primarily... Alnylam Pharmaceuticals, Inc. is a biopharmaceutical company primarily dedicated to the discovery, development, and commercialization of innovative therapeutic solutions leveraging ribonucleic acid interference (RNAi) technology. Its robust pipeline of RNAi-based treatments addresses a range of critical therapeutic areas, including inherited genetic disorders, cardio-metabolic conditions, hepatic infectious diseases, and central nervous system (CNS) and ocular disorders. Currently, Alnylam offers several approved therapies: ONPATTRO (patisiran) for adults suffering from polyneuropathy associated with hereditary transthyretin-mediated amyloidosis; GIVLAARI for adult patients with acute hepatic porphyria (AHP); and OXLUMO (lumasiran) for primary hyperoxaluria type 1 (PH1). Beyond its commercial portfolio, the company maintains an active development pipeline. Key investigational therapies include givosiran, aimed at adolescent patients with AHP; patisiran, being explored for transthyretin amyloidosis (ATTR) with cardiomyopathy; cemdisiran for complement-mediated disorders; ALN-AAT02 for AAT deficiency-associated liver disease; ALN-HBV02 for chronic hepatitis B virus infection; Zilebesiran for hypertension; and ALN-HSD for non-alcoholic steatohepatitis (NASH). Additionally, other candidates such as Fitusiran for hemophilia and bleeding disorders, Inclisiran for hypercholesterolemia, an expanded indication for lumasiran for advanced PH1 and recurrent kidney stones, and vutrisiran for ATTR amyloidosis (currently in Phase 3 clinical trials) are also progressing. Alnylam also engages in strategic alliances with other pharmaceutical leaders. Notable collaborations include those with Regeneron Pharmaceuticals, Inc., focused on discovering and developing RNAi therapeutics for ocular and CNS targets, and with Sanofi Genzyme for broader RNAi therapeutic development and commercialization efforts. Further licensing and partnership agreements are in place with entities such as Novartis AG, Vir Biotechnology, Inc., Dicerna Pharmaceuticals, Inc., Ionis Pharmaceuticals, Inc., and PeptiDream, Inc. Established in 2002, Alnylam Pharmaceuticals maintains its corporate headquarters in Cambridge, Massachusetts.
Aandeelprijs
$234.02
Laatst gesynchroniseerd: 2026-10-19
Marktkapitalisatie
$31.31B
Verandering (1 dag)
0.94%
Verandering (1 jaar)
-52.36%
Land
US
Handel Alnylam Pharmaceuticals, Inc. (ALNY)
Categorie
Healthcare
Operationele marge voor Alnylam Pharmaceuticals, Inc. (ALNY)
Operationele marge op October 2026 TTM: 20.81%
Volgens de meest recente financiële rapporten en aandelenkoers van Alnylam Pharmaceuticals, Inc. is de huidige operationele marge (TTM) 20.81%. Eind 2023 had het bedrijf een operationele marge van -15.43%.
Geschiedenis van de operationele marge van Alnylam Pharmaceuticals, Inc. van 2002 tot 2026
Operationele marge aan het einde van elk jaar
| Jaar | Operationele Marge | Wijzigen |
|---|---|---|
| 2026 (TTM) | 20.81% | -364.42% |
| 2024 | -7.87% | -49.00% |
| 2023 | -15.43% | -79.61% |
| 2022 | -75.68% | -9.83% |
| 2021 | -83.93% | -50.07% |
| 2020 | -168.09% | -60.68% |
| 2019 | -427.50% | -60.69% |
| 2018 | -1,087.56% | 95.53% |
| 2017 | -556.20% | -38.22% |
| 2016 | -900.33% | 25.00% |
| 2015 | -720.27% | -10.08% |
| 2014 | -800.97% | 306.48% |
| 2013 | -197.05% | 1.57% |
| 2012 | -194.01% | 192.89% |
| 2011 | -66.24% | 50.37% |
| 2010 | -44.05% | -7.96% |
| 2009 | -47.86% | 65.32% |
| 2008 | -28.95% | -84.19% |
| 2007 | -183.07% | 24.81% |
| 2006 | -146.68% | -80.71% |
| 2005 | -760.53% | 0.84% |
| 2004 | -754.18% | -94.70% |
| 2003 | -14,236.93% | 0.00% |
| 2002 | 0.00% | 0.00% |
Operationele marge van vergelijkbare bedrijven of concurrenten
| Bedrijf | Operationele Marge | Verschil in operationele marge | Land |
|---|---|---|---|
| 38.59% | -98.15% |
US
|
|
| -149.01% | -107.16% |
US
|
|
| 25.57% | -98.77% |
AU
|
|
| 0.00% | - |
CH
|
|
| 28.81% | -98.62% |
NL
|
Wat is de Operationele marge van een bedrijf?
De Operationele marge is een belangrijke indicator om de winstgevendheid van een bedrijf te beoordelen. Hogere operationele marges zijn over het algemeen beter omdat ze aangeven dat een bedrijf zijn producten of diensten veel duurder kan verkopen dan de productiekosten. De Operationele marge wordt berekend door de winst van een bedrijf te delen door de omzet.