AOTI, Inc. specializes in creating and marketing healthcare technologies... AOTI, Inc. specializes in creating and marketing healthcare technologies specifically designed for treating persistent and hard-to-heal wounds. Among its offerings are the innovative Topical Wound Oxygen (TWO2) Therapy and the NEXA Negative Pressure Wound Therapy (NPWT) System. Michael Stephen Griffiths founded the company in 2006, and its main office is located in Oceanside, California.