Alnylam Pharmaceuticals, Inc.
ALNY
Classement en actions
#773
Alnylam Pharmaceuticals, Inc. is a biopharmaceutical company primarily... Alnylam Pharmaceuticals, Inc. is a biopharmaceutical company primarily dedicated to the discovery, development, and commercialization of innovative therapeutic solutions leveraging ribonucleic acid interference (RNAi) technology. Its robust pipeline of RNAi-based treatments addresses a range of critical therapeutic areas, including inherited genetic disorders, cardio-metabolic conditions, hepatic infectious diseases, and central nervous system (CNS) and ocular disorders. Currently, Alnylam offers several approved therapies: ONPATTRO (patisiran) for adults suffering from polyneuropathy associated with hereditary transthyretin-mediated amyloidosis; GIVLAARI for adult patients with acute hepatic porphyria (AHP); and OXLUMO (lumasiran) for primary hyperoxaluria type 1 (PH1). Beyond its commercial portfolio, the company maintains an active development pipeline. Key investigational therapies include givosiran, aimed at adolescent patients with AHP; patisiran, being explored for transthyretin amyloidosis (ATTR) with cardiomyopathy; cemdisiran for complement-mediated disorders; ALN-AAT02 for AAT deficiency-associated liver disease; ALN-HBV02 for chronic hepatitis B virus infection; Zilebesiran for hypertension; and ALN-HSD for non-alcoholic steatohepatitis (NASH). Additionally, other candidates such as Fitusiran for hemophilia and bleeding disorders, Inclisiran for hypercholesterolemia, an expanded indication for lumasiran for advanced PH1 and recurrent kidney stones, and vutrisiran for ATTR amyloidosis (currently in Phase 3 clinical trials) are also progressing. Alnylam also engages in strategic alliances with other pharmaceutical leaders. Notable collaborations include those with Regeneron Pharmaceuticals, Inc., focused on discovering and developing RNAi therapeutics for ocular and CNS targets, and with Sanofi Genzyme for broader RNAi therapeutic development and commercialization efforts. Further licensing and partnership agreements are in place with entities such as Novartis AG, Vir Biotechnology, Inc., Dicerna Pharmaceuticals, Inc., Ionis Pharmaceuticals, Inc., and PeptiDream, Inc. Established in 2002, Alnylam Pharmaceuticals maintains its corporate headquarters in Cambridge, Massachusetts.
Prix de l'action
$234.02
Dernière synchronisation: 2026-10-19
Capitalisation boursière
$31.31B
Changement (1 jour)
0.94%
Changement (1 an)
-52.36%
Pays
US
Échange Alnylam Pharmaceuticals, Inc. (ALNY)
Catégorie
Healthcare
Marge opérationnelle de Alnylam Pharmaceuticals, Inc. (ALNY)
Marge opérationnelle au October 2026 TTM : 20.81%
Selon les derniers rapports financiers et le cours de l'action de Alnylam Pharmaceuticals, Inc., la marge opérationnelle actuelle (TTM) est de 20.81%. À la fin de 2023, elle était de -15.43%.
Historique de la marge opérationnelle pour Alnylam Pharmaceuticals, Inc. de 2002 à 2026
Marge opérationnelle à la fin de chaque année
| Année | Marge opérationnelle | Changez |
|---|---|---|
| 2026 (TTM) | 20.81% | -364.42% |
| 2024 | -7.87% | -49.00% |
| 2023 | -15.43% | -79.61% |
| 2022 | -75.68% | -9.83% |
| 2021 | -83.93% | -50.07% |
| 2020 | -168.09% | -60.68% |
| 2019 | -427.50% | -60.69% |
| 2018 | -1,087.56% | 95.53% |
| 2017 | -556.20% | -38.22% |
| 2016 | -900.33% | 25.00% |
| 2015 | -720.27% | -10.08% |
| 2014 | -800.97% | 306.48% |
| 2013 | -197.05% | 1.57% |
| 2012 | -194.01% | 192.89% |
| 2011 | -66.24% | 50.37% |
| 2010 | -44.05% | -7.96% |
| 2009 | -47.86% | 65.32% |
| 2008 | -28.95% | -84.19% |
| 2007 | -183.07% | 24.81% |
| 2006 | -146.68% | -80.71% |
| 2005 | -760.53% | 0.84% |
| 2004 | -754.18% | -94.70% |
| 2003 | -14,236.93% | 0.00% |
| 2002 | 0.00% | 0.00% |
Marge opérationnelle pour des entreprises similaires ou concurrentes
| Entreprise | Marge opérationnelle | Différence de Marge Opérationnelle | Pays |
|---|---|---|---|
| 38.59% | -98.15% |
US
|
|
| -149.01% | -107.16% |
US
|
|
| 25.57% | -98.77% |
AU
|
|
| 0.00% | - |
CH
|
|
| 28.81% | -98.62% |
NL
|
Qu'est-ce que la Marge opérationnelle d'une entreprise ?
La Marge opérationnelle est un indicateur clé pour évaluer la rentabilité d'une entreprise. Une marge d'exploitation plus élevée est généralement préférable car elle montre qu'une entreprise peut vendre ses produits ou services bien au-dessus de leurs coûts de production. Elle se calcule en divisant les bénéfices par le chiffre d'affaires.